Periodontal Disease is the number one cause of tooth loss in adults.  When plaque bacteria is not controlled by Home Care and Routine Preventive Cleanings, it begins to harden on the tooth, creating a shell of Tartar or Calculus.  As this layer expands, the gingival tissue becomes swollen and tender.  The infected gingiva begins to separate from the tooth causing a deep pocket between the gum and tooth structure.  The Periodontal Pocket becomes deeper with time, and when left untreated, creates the risk of losing an adult tooth.  

The loss of a tooth due to gum disease can be prevented.  Along with Scaling & Root Planing, Arestin fights the bacteria that causes gum disease.   Periodontal Disease is an infection caused by bacteria, and like other infections, it can be treated with an antibiotic.  Unlike antibiotics that are swallowed, Arestin is a powder that your Dentist or Hygienist places directly into the infected pockets around your tooth after completing Scaling & Root Planing.  Arestin powder contains tiny microspheres of the antibiotic minocycline, which is released over time into the infected pocket.  This means Arestin keeps fighting plaque bacteria after the patient has left the Dentist's chair. Arestin kills the bacteria most commonly associated with Periodontal Disease and has been shown to significantly reduce the depth of Periodontal Pockets.

Arestin contains minocycline, a tetracycline derivative and should not be used in patients with tetracycline allergies, children, and women who are pregnant or nursing.  Minor side-effects experienced after placement may include headaches, swelling, flu like symptoms and mild pain.  These, however, occurred at a similar rate to patients who were given a placebo.


Arestin works together with Scaling & Root Planing to be nearly 3 times a more successful treatment than Quadrant Scaling alone.  Typically, local anesthesia is used for the patient's comfort.  By Scaling & Root Planing, the Dentist or Hygienist removes the hard bacterial Tartar that irritates the gums and causes infection.  Scaling & Root Planing alone, however, is often not enough to complete treatment.  Adding Arestin helps kill the bacteria that Scaling & Root Planing cannot reach and prevents new plaque from entering the healing pocket.  Arestin microspheres are painlessly added to the infected pocket using a special plastic applicator.  The Antibiotics are released over time, helping to keep bacteria from returning while the gum heals.  After three months, the patient returns for a Periodontal Maintenance appointment. The pocket depths are monitored for improvement.  If a pocket has improved but is still deeper than 5 mm and/or bleeding on probing, another dose of Arestin may be placed.

Post-Placement Instructions for  Arestin

  • Wait at least 10 days before using floss, toothpicks or other devices designed to clean between teeth or below the gum line.
  • Do not touch treated area for one week
  • Avoid eating hard, crunchy, or sticky foods for one week
  • After 10 days, begin to brush and floss as instructed by your Dentist or Hygienist
  • Increase Oral Home Care, and develop a daily routine.
  • Follow up with your Dentist or Hygienist in 3 months for your Periodontal Maintenance appointment.  At this time, the areas where Arestin was placed will be checked to monitor the gum's improvement.  If the pocket has improved but is still deeper than 5 mm and/or bleeding on probing, another dose of Arestin may be necessary.


To learn more about Arestin, click the link below:


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